Abstract: . . .  psycholinguistics Page 1 PLINX204 PSYCHOLINGUISTICS LANGUAGE ACQUISITION – 2006 - 7 Molecular genetic evidence (2) QTL Analysis and Dyslexia Basic reading: Stromswold, 2001; Plomin et al, 2000, 2002; Newbury et al, 2005; Snowling, 2000. Additional reading: Any of: Fisher et al, 1999; Francks et al, 2004; Stein et al, 2004; Suresh et al, 2006; Lefly & Pennington, 1996; Gallagher et al, 2000. 1. There is a contrast between single-gene effects such as that of FOXP2 in the KE family and multiple gene effects which are characteristic of e.g. stuttering and dyslexia (aspects of spoken and written language respectively), and other gradient phenomena. Such effects are typically investigated on the basis of QTL (Quantitative Trait Locus) analysis. A QTL is a region of DNA associated with a particular phenotypic trait (e.g. plant height). Though not necessarily genes themselves, QTLs are stretches of DNA that are closely linked to the genes that underlie the trait in question. 2. Dyslexia : “a developmental disorder selectively affecting a child’s ability to learn to read and write … affecting boys more often . . .
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